Extensive-phrase animal studies haven't been performed to evaluate the carcinogenic opportunity of codeine or of promethazine, nor are there other animal or human info about carcinogenicity, mutagenicity, or impairment of fertility with these agents.
This medication could make you a lot more delicate into the Solar. Restrict your time while in the sun. Stay clear of tanning booths and sunlamps. Use sunscreen and dress in protecting outfits when outdoors. Tell your health care provider right away if you can get sunburned or have skin blisters/redness.
The amount of drugs that you choose to get depends on the strength in the medication. Also, the quantity of doses you take on a daily basis, enough time permitted concerning doses, as well as period of time you take the medication depend on the clinical dilemma for which you are using the medicine.
Keep away from using Promethazine HCl and Codeine Phosphate Oral Resolution in adolescents twelve to eighteen a long time of age who produce other possibility aspects that may raise their sensitivity to the respiratory depressant consequences of codeine.
Promethazine HCl and Codeine Phosphate Oral Solution is indicated to the temporary reduction of coughs and upper respiratory indications linked to allergy or the widespread chilly in patients eighteen a long time of age and older.
An elevated threat of specific malformations with codeine publicity like respiratory malformations, spina bifida and congenital coronary heart defects have been described in certain scientific tests.
The following severe adverse reactions are described, or explained in better detail, in other sections:
A healthcare Expert needs to be consulted right before getting any drug, transforming any diet plan or commencing or discontinuing any program of treatment method.
Bluish lips or pores and skin chills clay-colored stools chilly sweats confusion cough dark urine reduce in the frequency of urination lower inside the urine quantity diarrhea tricky or troubled breathing trouble in passing urine (dribbling) dizziness dizziness, faintness, or lightheadedness when acquiring up from lying or sitting down position rapid, pounding, or irregular heartbeat or pulse experience of warmth fever headache large fever hives or welts, itching, or rash increased sweating irregular, rapid or sluggish, or shallow respiration large, hive-like swelling to the deal with, eyelids, lips, tongue, throat, palms, legs, feet, or sexual intercourse organs lack of urge for food lack of bladder Handle nausea noisy respiration not breathing agonizing urination pale or blue lips, fingernails, or pores and skin rectal bleeding redness of your facial area, neck, arms, and infrequently, higher upper body redness of your skin observing, hearing, or feeling issues that are not there seizures intense muscle stiffness shakiness while in the Promethazine codeine syrup legs, arms, or fingers abdomen soreness perspiring tightness in the chest tiredness trembling or shaking in the fingers or toes unpleasant breath odor abnormal tiredness or weak spot unusually pale skin vomiting of blood yellow eyes or pores and skin Get unexpected emergency aid right away if any of the following indicators of overdose come about:
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The results of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are elaborate, necessitating watchful consideration of the consequences around the father or mother drug, codeine, along with the active metabolite, morphine.
This merchandise could contain inactive substances, that may induce allergic reactions or other issues. Talk with your pharmacist for more specifics.
Codeine has good antitussive action, Whilst a lot less than that of morphine at equal doses. It truly is used in preference to morphine, mainly because Unintended effects are infrequent at the standard antitussive dose of codeine.
Dosing The dose of the medicine is going to be unique for different individuals. Abide by your medical professional's orders or the Instructions about the label. The following information and facts features only the average doses of the medication. When your dose is different, will not transform it Except your physician tells you to do so.